EMBO Member
1933 – 2020
EMBO 1989
My laboratory's main interest is the germline genetics of thyroid cancer, colorectal cancer, AML and CLL. Predisposing mutations are sought by linkage and association studies and next generation sequencing strategies. Thyroid cancer is a disease showing high heritability, yet few predisposing genes are known. Much of the predisposition comes from multiple low-penetrant mutations that are often non-coding RNAs, including microRNAs.
Keywords: Human disease genes / cancer genetics / cancer biology / diagnosis / counselling
Subject area(s): Microbiology, Virology & Pathogens | Molecular Medicine | RNA