EMBO Member
Weizmann Institute of Science, Rehovot | Israel
EMBO 1995 | YipC 04–07
Our main topic is next-generation sequencing (NGS) elucidation of human diseases. This includes the widely-used GeneCards suite, a set of databases and tools for human genes, pathways and diseases. A recent focus is NGS interpretation via VarElect, with whole genome sequencing preparedness (data on enhancers and ncRNA genes). A parallel thread is computer-simulated models for pre-RNA prebiotic evolution.
Keywords: Next generation sequencing interpretation / gene and disease databases / molecular recognition / bioinformatics / regulatory elements / systems medicine / systems prebiology / origin of life
Subject area(s): Genomic & Computational Biology | Systems Biology | Evolution & Ecology