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EMBO Member

Friedrich Frischknecht

Universität Heidelberg | Germany

EMBO 2022

Plasmodium formation, migration and attenuation

Our group studies different aspects of malaria parasite biology with a focus on parasite transmission to and from mosquitoes. We mainly use a rodent-infecting malaria parasite to investigate membrane or cytoskeleton-associated proteins and their roles in parasite formation and motility. We employ reverse genetics to modify or delete genes and state-of-the-art microscopy to understand function and to explore new types of experimental vaccines.

Keywords: Plasmodium / cytoskeleton / molecular parasitology / gliding motility / vaccine research

Subject area(s): Cell & Tissue Architecture | Microbiology, Virology & Pathogens | Molecular Medicine

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