EMBO Member

Fritz Thoma

Zurich | Switzerland

EMBO 1996

Chromatin structure and DNA repair in yeast

My research included: (i) Histone H1 dependent folding of DNA into nucleosomes and chromatin fibers, (ii) nucleosome positioning in yeast, (iii) chromatin structure of yeast genes and the fate of nucleosomes during transcription, (v) DNA damage formation by UV light in chromatin, (vi) DNA repair by photolyase and nucleotide excision repair as a model system for how proteins access DNA in functionally distinct chromatin regions.

Keywords: Chromatin / nucleosomes / transcription / DNA repair / yeast

Subject area(s): Chromatin & Transcription | Genome Stability & Dynamics | Structural Biology & Biophysics