EMBO Member
Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid | Spain
EMBO 2021
Our research activity has focused on the study of the OXPHOS system, showing that the respiratory complexes are organized into supercomplexes that co-exist dynamically with the free complexes. This optimizes the cell metabolism while minimizing ROS production. We have also explored the role of ROS as a mitochondrial second messenger, the relevance of mtDNA genetic variability, and the impact of mitochondria on organism physio-pathology.
Keywords: Cellular metabolism / mitochondrial genetics / mitochondrial biochemistry / cardiovascular physiology / OXPHOS regulation / mtDNA / reactive oxygen species (ROS)
Subject area(s): Cellular Metabolism | Genomic & Computational Biology | Membranes & Transport | Molecular Medicine | Proteins & Biochemistry | Proteins & Biochemistry | Cellular Metabolism | Genomic & Computational Biology | Membranes & Transport | Molecular Medicine | Molecular Medicine | Proteins & Biochemistry | Proteins & Biochemistry | Molecular Medicine | Membranes & Transport | Genomic & Computational Biology | Cellular Metabolism | Proteins & Biochemistry | Molecular Medicine | Membranes & Transport | Genomic & Computational Biology | Cellular Metabolism | Proteins & Biochemistry | Molecular Medicine | Membranes & Transport | Genomic & Computational Biology | Cellular Metabolism | Proteins & Biochemistry | Molecular Medicine | Membranes & Transport | Genomic & Computational Biology | Cellular Metabolism | Membranes & Transport | Genomic & Computational Biology | Cellular Metabolism | Proteins & Biochemistry | Molecular Medicine | Membranes & Transport | Genomic & Computational Biology | Cellular Metabolism